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Poster-High Concentration Protein Suspensions: A Case Study for Subcutaneous Delivery of Bevacizumab
Our scientific poster presents a case study on the development of a high concentration protein suspension (400-500 mg/mL) suitable for subcutaneous delivery of therapeutic proteins. Using Bevacizumab as a model system, we explore key considerations for successful product development and design.
Key Learnings:
• Formulation and process design to produce stable spray dried protein particles
• Particle engineering and vehicle selection to maximize the deliverable dose
• Considerations of both protein stability and suspension viscosity in the design of syringable high concentration protein suspensions
About Serán
Serán BioScience, LLC, is a science-driven Drug Development Partner, recognized as a world leader in drug development. Utilizing a foundation of physical and chemical science, Serán designs robust formulations and engineered solutions to some of the industry's toughest drug product problems. Our experience and background cover a wide range of pharmaceutical manufacturing concepts bringing our world-class expertise to you and your drug product. Serán’s team has decades of experience developing complex drug molecules into enabling medicines. With every addition to our team, we further our commitment to our clients’ success. From preclinical to GMP and beyond, Serán is here to support you and your drug product every step of the way.
For more information, visit www.Seranbio.com or email us at hello@seranbio.com.
Contact
Serán BioScience, LLC
63047 Layton Ave, Bend, OR 97701 USA
www.seranbio.com
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